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Paroxysmal dyskinesia
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Paroxysmal dyskinesia : ウィキペディア英語版
Paroxysmal dyskinesia
The paroxysmal dyskinesias (PD) are a group of movement disorders characterized by attacks of hyperkinesia with intact consciousness.〔Blueprints Neurolgy, 2nd ed.〕 Paroxysmal dyskinesia is a rare disorder, however the number of individuals it affects remains unclear. There are three different subtypes of PD that include paroxysmal kinesigenic dyskinesia, paroxysmal non-kinesigenic dyskinesia, and paroxysmal exercise-induced dyskinesia. Other neurological diseases have similar symptoms to PD, such as epilepsy and Parkinson's. The different subtypes make accurate and quick diagnosis of PD challenging. Thus, PD is often under reported and misdiagnosed, making it difficult to accurately study its prevalence in human populations. Onset of PD is usually in late childhood to early adolescence. New drug regimens help treat symptoms of PD, but no cure for the disorder is known.
==Different Forms of Paroxysmal Dyskinesia==
The paroxysmal dyskinesias are mainly classified by their triggers and on the basis of the duration and frequency of the attacks. The three main types are paroxysmal kinesigenic dyskinesia (PKD), paroxysmal non-kinesigenic dyskinesia (PNKD) and paroxysmal exercise-induced (exertion-induced) dyskinesia (PED).
===Paroxysmal Kinesigenic Dyskinesia (PKD)===
This is characterized by attacks of involuntary movements (dystonia, chorea, or ballism), which are typically triggered by sudden voluntary movements, but can also be triggered by involuntary movements as well (for example, hyperventilating). These voluntary movements usually involve whole body activity such as standing, walking, and running. The age of onset is typically in childhood or early adolescence with most cases reporting improvement or complete remission with aging. Attacks last from seconds to minutes and are known to be at higher risk of occurring during stress, fear, cold, heat, or menstruation.
===Paroxysmal Non-kinesogenic Dyskinesia (PNKD)===
This is similar to PKD, characterizing as an episodic movement disorder, but is not triggered by voluntary movements. The attacks for PNKD are spontaneous and last from hours to days. It is an autosomal dominant disorder passing to nearly 50% of the offspring. Some predisposing factors include stress, excitement, alcoholic beverages, tea, and beverages with caffeine.
===Paroxysmal Exercise-induced Dyskinesia (PED)===
This is an extremely rare type of paroxysmal dyskinesia characterized by sudden, involuntary, dystonic movements, often including repetitive twisting motions and painful posturing. The attacks are triggered by exercise and other physical exertion, and usually last from minutes to an hour. Attacks usually appear in the body part that is being exercised or exerted over a period of time, perhaps 10 to 15 minutes.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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